Invitrogen™ CD148 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5122136

Product Code. 17743534

Description

CD148 Polyclonal Antibody for Western Blot, ICC/IF, IHC (P)

CD148 is a highly glycosylated transmembrane protein of up to 250 kDa, containing eight fibronectin type III domains in the extracellular region and one tyrosine phosphatase domain in the cytoplasmic region. Expression is found broadly on fibroblasts, epithelial cells, lymphocytes (B, T and NK cells), and myeloid cells (monocytes and granulocytes). CD148 can dephosphorylate proteins such as LAT and PLC-gamma, and is involved in the downregulation of T cell activation. Conversely, CD148 expression can be upregulated following T cell activation.

Specifications

• Antigen: CD148
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PTPRJ
• Gene Alias: AI450271; BET; Byp; CD148; CD148 antigen; colon tumor susceptibility 1; density enhanced phosphatase-1; density-enhanced phosphatase 1; DEP1; DEP-1; HPTP beta-like tyrosine phosphatase; HPTP eta; HPTPeta; human density enhanced phosphatase-1; protein tyrosine phosphatase, receptor type J; protein tyrosine phosphatase, receptor type, J; protein tyrosine phosphatase, receptor type, J polypeptide; protein-tyrosine phosphatase eta; Protein-tyrosine phosphatase receptor type J; Ptpb2; PTPbeta2; Ptprj; Receptor-type tyrosine-protein phosphatase eta; R-PTP-ETA; RPTPJ; R-PTP-J; Scc1; Scc-1; Susceptibility to colon cancer 1; susceptibility to colon cancer 1, mouse, homolog of
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography, Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 19271, 5795
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.5 mg/mL
• Formulation: PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4
• Gene Accession No.: Q12913, Q64455
• Gene Symbols: PTPRJ
• Immunogen: Recombinant protein Density Enhanced Phosphatase 1. The antigen corresponds to amino acid range 1061-1293 of the target protein.
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG