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CD144 (VE-cadherin) Monoclonal Antibody (eBioBV13 (BV13)), eFluor™ 450, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 48-1441-80

Code : Z2

Additional Details : Weight : 0.25000kg

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Product Code. 15381750

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Description

Description

Description: The BV13 monoclonal antibody reacts with mouse VE-Cadherin (CD144). VE-Cadherin is a 120 kDa member of the type II Cadherin family, characterized by the presence of 5 extracellular cadherin domains (ECD), and anchored to the actin cytoskeleton through their cytoplasmic tail. VE-Cadherin mediates homophilic adhesion between neighbouring endothelial cells and is localized within specialized structures at cell-cell contacts, called adherens junctions. VE-Cadherin is expressed constitutively throughout the entire vasculature, and is required for numerous endothelial cell functions including migration, survival, contact-dependent growth inhibition and endothelial cell assembly into tubular structures. Furthermore, it is thought that VE-Cadherin+CD45- cells from the yolk sac or aorta-gonad-mesonephros (AGM) have the potential to give rise to hematopoietic cells. Applications Reported: This eBioBV13 (BV13) antibody has been reported for use in flow cytometric analysis. Applications Tested: This eBioBV13 (BV13) antibody has been tested by flow cytometric analysis of bEnd.3 cells. This can be used at less than or equal to 2 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test.

CD144 (VE-cadherin) Monoclonal antibody specifically detects CD144 (VE-cadherin) in Mouse samples. It is validated for Flow Cytometry.
Specifications

Specifications

CD144 (VE-cadherin)
Monoclonal
0.2 mg/mL
PBS with 0.09% sodium azide; pH 7.2
P55284
Cdh5
Affinity chromatography
RUO
12562
4° C, store in dark, DO NOT FREEZE!
Liquid
Flow Cytometry
eBioBV13 (BV13)
eFluor 450
Cdh5
7B4; 7B4 antigen; 7B4/cadherin-5; AA408225; cadherin 5; cadherin 5, type 2 (vascular endothelium); cadherin 5, type 2, VE-cadherin (vascular endothelium); cadherin 5, type 2, VE-cadherin (vascular epithelium); cadherin-5; cadherin-5; cd144 antigen; VE cadherin; Cd144; cd144 antigen; CDH5; cell-cell adhesion protein; endothelial-specific cadherin; vascular endothelial cadherin; vascular endothelial cadherin precursor; Vec; VEcad; VE-Cad; VE-cadherin; VECD
Rat
25 μg
Primary
Mouse
Antibody
IgG1 κ
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For Research Use Only.