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CD144 (VE-Cadherin) Rat anti-Mouse, Clone: eBioBV14 (BV14), eBioscience™

Rat Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-1442-82

UNSPSC : 12352200

Code : Z2

Additional Details : Weight : 0.01000kg

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Product Code. 15207237

  • £91.11 / 100µg


Estimated Shipment
07-08-2017
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Disclaimers:

For Research Use Only.


Specifications

Description

The BV14 monoclonal antibody reacts with mouse VE-Cadherin (CD144). VE-Cadherin is a 120kDa member of the type II Cadherin family, characterized by the presence of 5 extracellular cadherin domains (ECD), and anchored to the actin cytoskeleton through their cytoplasmic tail. VE-Cadherin mediates homophilic adhesion between neighbouring endothelial cells and is localized within specialized structures at cell-cell contacts, called adherens junctions. VE-Cadherin is expressed constitutively throughout the entire vasculature, and is required for numerous endothelial cell functions including migration, survival, contact-dependent growth inhibition and endothelial cell assembly into tubular structures. Furthermore, it is thought that VE-Cadherin+CD45- cells from the yolk sac or aorta-gonad-mesonephros (AGM)+ have the potential to give rise to hematopoietic cells. Cross-blocking experiments suggest that BV14 recognizes a different epitope than another mouse VE-Cadherin monoclonal antibody, BV13.
Description & Specifications

Specifications

CD144 (VE-Cadherin)
eBioBV14 (BV14)
Unlabeled
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Rat
100μg
Store at 2-8°C.
Monoclonal
Western Blot
0.5mg/mL
Purified
Cadherin 5
IgG2b
RUO
Primary
Murine