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CD138 (Syndecan-1) Mouse, anti-Human, FITC, Clone: MI15, STEMCELL Technologies

Mouse Monoclonal Antibody

Brand:  Stemcell Technologies 60003FI

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Product Code. 17128341

  • £395.55 / 100 tests

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Description

Description

  • The MI15 antibody reacts with an extracellular epitope on CD138 (Syndecan-1), an ∼85 - 95 kDa type 1 transmembrane glycoprotein expressed on the surface of pre-B cells, immature B cells, and normal and malignant plasma cells (but not mature circulating B cells), as well as on non-hematopoietic cells such as embryonic mesenchymal cells, endothelial, epithelial and neural cells
  • CD138 expression is used as a diagnostic marker for several types of tumors
  • CD138 is thought to act primarily as a receptor that modulates cell proliferation, cell migration and cell-matrix associations by linking the extracellular matrix to the cytoskeleton
  • Theparin sulfate and chondroitin sulfate moieties attached to CD138 associate with several proteins, including collagens, fibronectin, tenascin, thrombospondin and certain cytokines
  • The MI15 antibody recognizes a different epitope than that of the clone DL-101 anti-CD138 antibody but blocks binding of clone B-B4
Specifications

Specifications

CD138 (Syndecan-1)
Monoclonal
FITC
100 Tests
Cynomolgus, Human, Rhesus Monkey
B Cells, Plasma
Immunohistochemistry, Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence
MI15
Mouse
Primary
IgG1 κ
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