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CD135 (Flt3) Monoclonal Antibody (BV10A4H2), APC, eBioscience™, Invitrogen™
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Mouse Monoclonal Antibody

£89.25 - £241.00

Tekniske data

Antigen CD135 (Flt3)
Clone BV10A4H2
Concentration 5 μL/Test
Applications Flow Cytometry
Classification Monoclonal
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Produkter 2
Produktkode Brand Quantity Pris Antal & tilgængelighed  
Produktkode Brand Quantity Pris Antal & tilgængelighed  
15538006
Dokumentvisning
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Invitrogen
17-1357-41 		25 Tests This item is currently unavailable or has been discontinued.
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15548006
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Dokumentvisning
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Invitrogen™
17-1357-42 		100 Tests
£241.00
100 tests
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Beskrivelse

Beskrivelse

Description: The BV10A4H2 monoclonal antibody reacts with human CD135, also known as Flk2/Flt3. A member of the tyrosine kinase receptor family, this 135-150 kDa molecule is expressed by multipotential progenitor cells including primitive B cell and myelomonocytic progenitors in fetal liver and adult bone marrow. Applications Reported: The BV10A4H2 antibody has been reported for use in flow cytometric analysis. Applications Tested: This BV10A4H2 antibody has been pre-titrated and tested by flow cytometric analysis of REH cell line. This can be used at 5 μL (0.5 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Excitation: 633-647 nm; Emission: 660 nm; Laser: Red Laser. Filtration: 0.2 μm post-manufacturing filtered.

FLT3 is a tyrosine protein kinase that is a member of the growth factor receptor tyrosine kinase family. The receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia.
Tekniske data

Tekniske data

CD135 (Flt3)
5 μL/Test
Monoclonal
Liquid
RUO
P36888
FLT3
IgG1
Affinity chromatography
Antibody
BV10A4H2
Flow Cytometry
APC
Mouse
Human
2322
BV-173 leukemic cell line
Primary
4° C, store in dark, DO NOT FREEZE!
FLT3
Videoer
SDS
Dokumenter

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For Research Use Only.

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