CD122 Rat anti-Mouse, Clone: TM-b1 (TM-beta1), Functional Grade, eBioscience™

Rat Monoclonal Antibody, Functional Grade

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 16-1222-81

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15238547

Quantity Price
1 £ 66.65 / 50µg
Estimated Shipment date
from Supplier 04-05-2017
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Description and Specification

Specification

Applications Flow Cytometry
Applications Functional Assay
Conjugate Unlabeled
Primary or Secondary Primary
Concentration 1mg/mL
Gene Alias Interleukin-2 Receptor beta, IL-2Rb
Regulatory Status RUO
Species Reactivity Mouse
Storage Requirements Store at 2-8°C.
Clone TM-b1 (TM-beta1)
Isotype IgG2b
Monoclonal or Polyclonal Monoclonal
Host Species Rat
Antigen CD122
Quantity 50μg
Format Purified
Formulation aqueous buffer, no sodium azide

The TM-b1 monoclonal antibody reacts with mouse CD122, the 90-110kDa interleukin-2 receptor beta chain (IL-2R beta). CD122 is expressed by NK cells and some T cells in the periphery, and is upregulated by activation. CD122 associates with CD25 and CD132 (common gamma chain) to form the high affinity IL-2 receptor. High affinity binding of IL-2 to the IL-2 receptor is inhibited by the TM-b1 antibody.