CD122/IL2RB Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 13602-1-AP-20UL

Product Code. 16881894

Description

CD122 (Interleukin 2 receptor) is involved in T cell-mediated immune responses, primarily expressed in the hematopoietic system and is present in 3 forms. The low affinity form of CD122 is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from CD122. The protein encoded by the CD122 gene represents the beta subunit and is a type I membrane protein. Diseases associate with CD122 protein dysfunction include oligoarticular juvenile idiopathic arthritis and rheumatoid factor negative juvenile idiopathic arthritis.

Specifications

• Antigen: CD122/IL2RB
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: IL2RB
• Gene Alias: CD122, IL 2 receptor subunit beta, IL 2R subunit beta, IL 2RB, IL2RB, interleukin 2 receptor, beta, P70 75, p75
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 16185, 3560
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunohistochemistry (Paraffin)
• Concentration: 0.15 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P14784, P16297
• Gene Symbols: IL2RB
• Immunogen: CD122/IL2RB Fusion Protein Ag3929
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Mouse, Human
• Product Type: Antibody
• Isotype: IgG