CD120b (TNF Receptor II) Armenian Hamster anti-Mouse, Clone: TR75-54, eBioscience™

Armenian Hamster Monoclonal Antibody

Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-1203-81

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg

Disclaimers: For Research Use Only.

Product Code. 15257187

Quantity Price
1 £ 60.53 / 50µg
Estimated Shipment date
from Supplier 04-05-2017
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Description and Specification


Gene Alias TNFR2p80, TNF RII, TNFRII
Applications Enzyme Linked Immunosorbent Assay
Applications Flow Cytometry
Applications Functional Assay
Applications Immunoprecipitation
Applications Western Blotting
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Species Reactivity Mouse
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Antigen CD120b (TNF Receptor II)
Regulatory Status RUO
Host Species Armenian Hamster
Clone TR75-54
Storage Requirements Store at 2-8°C.
Isotype IgG
Quantity 50μg
Conjugate Unlabeled
Format Purified
Concentration 0.5mg/mL

The TR75-54 monoclonal antibody reacts with mouse Tumor Necrosis Factor Receptor II (TNFRII, TNFR-p80, TNFRSF1B, CD120b). TNFRII is expressed in a variety of cell types and strongly expressed on stimulated T and B lymphocytes. TNFRII is the main TNF receptor found on circulating T cells and is the major mediator of autoregulatory apoptosis in CD8+ cells. The soluble TNF receptors are truncated forms of cell surface receptors with neutralizing activity on both TNF-α and TNF-β. It has been suggested that the proinflammatory and immunosuppressive properties of TNF segregate at the level of its receptors and that the pool of TNF bound to soluble receptors could represent a reservoir to control the TNF release.