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CD120b (TNF Receptor II) Armenian Hamster anti-Mouse, Clone: TR75-54, eBioscience™

Armenian Hamster Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-1203-81

UNSPSC : 12352200

Code : Z2

Additional Details : Weight : 0.01000kg

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Product Code. 15257187

  • £60.53 / 50µg


Estimated Shipment
07-07-2017
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Disclaimers:

For Research Use Only.


Specifications

Description

The TR75-54 monoclonal antibody reacts with mouse Tumor Necrosis Factor Receptor II (TNFRII, TNFR-p80, TNFRSF1B, CD120b). TNFRII is expressed in a variety of cell types and strongly expressed on stimulated T and B lymphocytes. TNFRII is the main TNF receptor found on circulating T cells and is the major mediator of autoregulatory apoptosis in CD8+ cells. The soluble TNF receptors are truncated forms of cell surface receptors with neutralizing activity on both TNF-α and TNF-β. It has been suggested that the proinflammatory and immunosuppressive properties of TNF segregate at the level of its receptors and that the pool of TNF bound to soluble receptors could represent a reservoir to control the TNF release.
Description & Specifications

Specifications

CD120b (TNF Receptor II)
TR75-54
Unlabeled
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Armenian Hamster
50μg
Store at 2-8°C.
Monoclonal
Western Blot
0.5mg/mL
Purified
TNFR2p80, TNF RII, TNFRII
IgG
RUO
Primary
Murine