CD11c Armenian Hamster anti-Mouse, PE-Cy7, Clone: N418, eBioscience™

Armenian Hamster Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 25-0114-81

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.25000kg



Disclaimers: For Research Use Only.

Product Code. 15390890

Quantity Price
1 £ 111.78 / 50µg
EU Stock 9
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Description and Specification

Specification

Antigen CD11c
Gene Alias Integrin alpha X, Integrin aX, ITGAX, p150/95, leu M5 alpha
Species Reactivity Mouse
Clone N418
Isotype IgG
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
Host Species Armenian Hamster
Concentration 0.2mg/mL
Monoclonal or Polyclonal Monoclonal
Conjugate PE-Cy7
Regulatory Status RUO
Quantity 50μg
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Applications Flow Cytometry
Primary or Secondary Primary

The N418 monoclonal antibody reacts with mouse CD11c, the integrin alpha X. CD11c non-covalently associates with beta 2 integrin to form the CD11c/CD18 heterodimer. CD11c is expressed by dendritic cells, a subset of Intestinal Intraepithelial Lymphocytes (IEL) and some activated T cells. CD11c/CD18 binds to CD54, iC3b and fibrinogen and plays a role in leukocyte adhesive interactions. N418 binds to CD11c on splenic dendritic cells in the T-dependent areas of mouse spleen and precipitates a 150, 90kDa heterodimer.