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CD11a (LFA-1alpha), clone: HI111, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-0119-80

Code : Z2

Additional Details : Weight : 0.01000kg

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Product Code. 15216817

  • £31.01 / 25µg


Estimated Shipment
29-06-2018
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Description

Description

Description: The HI111 monoclonal antibody reacts with human CD11a, the 180kDa integrin alphaL, also known as the lymphocyte function associated antigen-1 (LFA-1) alpha chain. LFA-1, formed by non-covalent association of CD11a with CD18 (integrin beta2), serves as an important adhesion molecule involved in lymphocyte and granulocyte function. CD54 (ICAM-1), CD102 (ICAM-2), and CD50 (ICAM-3) are ligands for LFA-1. CD11a is expressed by all leukocytes.Applications Reported: This HI111 antibody has been reported for use in flow cytometric analysis, and immunohistology staining of frozen tissue sections. It has also been reported in blocking of CD11a function in mixed lymphocyte reactions. (Please use Functional Grade purified HI111, cat. 16-0119, in functional assays.).Applications Tested: The HI111 antibody has been tested by flow cytometric analysis of normal human peripheral blood cells. This can be used at less than or equal to 1 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest.Purity: Greater than 90%, as determined by SDS-PAGE.Aggregation: Less than 10%, as determined by HPLC.Filtration: 0.2μm post-manufacturing filtered.
Specifications

Specifications

CD11a
Monoclonal
0.5mg/mL
PBS with 0.09% sodium azide; pH 7.2
P20701
CD11 antigen-like family member A, LFA-1 alpha, LFA-1A, antigen CD11A p180, lymphocyte function-associated antigen 1 alpha polypeptide, integrin alpha-L
Murine
Affinity chromatography
RUO
Antibody
Monoclonal
Human
Immunohistochemistry (Frozen)
HI111
Unconjugated
ITGAL
Purified
ITGAL
IgG1, kappa
25μg
Store at 2-8°C.
Primary
3683
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