CD106 (VCAM-1) Mouse anti-Rat, Clone: eBioMR106 (MR106), eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 14-1060-85

UNSPSC: 12352200

Code: Z2

Additional Details:
Additional Details: Weight: 0.01000kg



Disclaimers: For Research Use Only.

Product Code. 15257157

Quantity Price
1 £ 152.25 / 500µg
EU Stock 2
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Description and Specification

Specification

Storage Requirements Store at 2-8°C.
Monoclonal or Polyclonal Monoclonal
Concentration 0.5mg/mL
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Antigen CD106 (VCAM-1)
Quantity 500μg
Gene Alias VCAM1, vascular cell adhesion molecule-1
Species Reactivity Rat
Primary or Secondary Primary
Isotype IgG1
Applications Flow Cytometry
Applications Immunohistochemistry (Frozen)
Applications Immunoprecipitation
Applications Western Blotting
Host Species Mouse
Clone eBioMR106 (MR106)
Format Purified
Conjugate Unlabeled
Regulatory Status RUO

The eBioMR106 monoclonal antibody reacts with rat CD106 (Vascular Cell Adhesion Molecule-1, VCAM-1), a 110kDa transmembrane glycoprotein expressed by myeloid lineage and bone marrow stromal cells. Endothelial cells constitutively express low levels of CD106 and further upregulate VCAM-1 upon cytokine stimulation. CD106 binds to integrin α4β1 (VLA-4, CD49d/CD29) and Integrin α4β7 (LPAM-1) and these interactions in the bone marrow and thymus are important for early lymphocyte and myeloid development. Cytokine-mediated upregulation of CD106 on endothelial cells suggests a role for this antigen in the inflammatory response.