CD100 (SEMA4D) Mouse anti-Human, Alexa Fluor 488, Clone: 133-1C6, eBioscience™

Mouse Monoclonal Antibody

Overview
Brand: Affymetrix eBioscience

Manufacturer Part Number: 53-1009-42

Code: NEW

Additional Details:
Additional Details: Weight: 0.23750kg



Disclaimers: For Research Use Only.

Product Code. 15510197

Quantity Price
1 £ 182.82 / 100 tests
EU Stock 1
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Description and Specification

Specification

Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Host Species Mouse
Concentration 5μL (0.25μg)/test
Regulatory Status RUO
Clone eBio133-1C6 (133-1C6)
Gene Alias Semaphorin 4D
Primary or Secondary Primary
Species Reactivity Human
Monoclonal or Polyclonal Monoclonal
Conjugate Alexa Fluor 488
Format Conjugated
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Isotype IgM
Antigen CD100 (SEMA4D)
Quantity 100 tests
Applications Flow Cytometry

The eBio133-1C6 monoclonal antibody reacts with human CD100, a member of the class IV semaphorin family also called sema4D. CD100 promotes angiogenesis, invasive growth, proliferation, and anti-apoptosis of cancer cells in vitro. Furthermore CD100 is a costimulatory molecule in adaptive immune responses by switching off negative signalling from CD72. In addition to CD72 another ligand is Plexin-B1. It has been shown that higher expression levels of CD100 are correlated with poor survival in soft tissue sarcoma patients. Expression is found in both hematopoietic and non-hematopoietic cells.CD100 is expressed on resting T cells and NK cells and B cell. CD100 can also exist as a soluble form.