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CD100 (SEMA4D) Mouse anti-Human, Alexa Fluor 488, Clone: 133-1C6, eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 53-1009-42

Code : NEW

Additional Details : Weight : 0.23750kg

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Product Code. 15510197

  • £182.82 / 100 tests


EU Stock 1
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Disclaimers:

For Research Use Only.


Description

Description

The eBio133-1C6 monoclonal antibody reacts with human CD100, a member of the class IV semaphorin family also called sema4D. CD100 promotes angiogenesis, invasive growth, proliferation, and anti-apoptosis of cancer cells in vitro. Furthermore CD100 is a costimulatory molecule in adaptive immune responses by switching off negative signalling from CD72. In addition to CD72 another ligand is Plexin-B1. It has been shown that higher expression levels of CD100 are correlated with poor survival in soft tissue sarcoma patients. Expression is found in both hematopoietic and non-hematopoietic cells.CD100 is expressed on resting T cells and NK cells and B cell. CD100 can also exist as a soluble form.
Specifications

Specifications

CD100 (SEMA4D)
eBio133-1C6 (133-1C6)
Alexa Fluor 488
Conjugated
Murine
100 Tests
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
Flow Cytometry
5μL (0.25μg)/test
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Semaphorin 4D
IgM
RUO
Primary
Human