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CD10 Mouse anti-Human, Biotin, Clone: eBioCB-CALLA (CB-CALLA), eBioscience™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 13-0106-82

UNSPSC : 12352200

Code : Z2

Additional Details : Weight : 0.25000kg

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Product Code. 15269439

  • £91.11 / 100µg


EU Stock 1
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Disclaimers:

For Research Use Only.


Specifications

Description

The eBioCB-CALLA monoclonal antibody recognizes human CD10 (CALLA, NEP, enkephalinase, Neprilysin), which is a 100 kDa, type II cell surface glycoprotein originally identified for its expression on most acute lymphoblastic leukemias (ALL). Subsequently, CD10 was shown to be the same molecule as the neutral endopeptidase (NEP), or KII-NA. CD10 is a Zn2+-dependent metallo-peptidase with endothelin, glucagon, gastrin, neurotensin and bradykinin included among its substrates. CD10 is involved in the regulation of chemotactic and inflammatory processes involving neutrophils. In B cells, CD10 regulates stromal cell-dependent B lymphopoiesis and expression has also been reported on mature B cells in germinal centres. In addition to the hematopoietic compartment, other major sites of CD10 expression are the brush border of enterocytes and renal tubules and glomeruli. There is partial blocking of the eBioCB-CALLA and MEM-78 monoclonal antibodies indicating that they recognize similar epitopes.
Description & Specifications

Specifications

CD10
eBioCB-CALLA (CB-CALLA)
Biotin
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Murine
100μg
Store at 2-8°C. Do not freeze.
Monoclonal
Flow Cytometry
0.5mg/mL
Conjugated
Common Acute Lymphocytic Leukemia antigen (CALLA), Neprilysin
IgG2b
RUO
Primary
Human