Invitrogen™ CCRD6 Monoclonal Antibody (196124)

Rat Monoclonal Antibody

Brand:  Invitrogen™ MA560975

Product Code. 30535218

Description

Reconstitute at 0.5 mg/mL in sterile PBS.

This gene encodes a beta chemokine receptor, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptor-mediated signal transduction are critical for the recruitment of effector immune cells to the inflammation site. This gene is expressed in a range of tissues and hemopoietic cells. The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors. This receptor appears to bind the majority of beta-chemokine family members; however, its specific function remains unknown. This gene is mapped to chromosome 3p21.3, a region that includes a cluster of chemokine receptor genes.

Specifications

• Antigen: CCRD6
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with trehalose and no preservative
• Gene Accession No.: O00590
• Gene Symbols: ACKR2
• Immunogen: RBL-1 rat basophilic leukemia cell line transfected with human CC Chemokine Receptor D6, Met1-Ala384.
• Quantity: 500 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a

• Applications: Flow Cytometry
• Clone: 196124
• Conjugate: Unconjugated
• Gene: ACKR2
• Gene Alias: Ackr2; AI464239; Atypical chemokine receptor 2; C-C chemokine receptor D6; Ccbp2; CC-chemokine-binding receptor JAB61; CCR10; CCR10-related receptor; CCR9; chemokine (C-C motif) receptor 9; chemokine (C-C) receptor 9; chemokine binding protein 2; chemokine decoy receptor D6; chemokine receptor CCR-10; Chemokine receptor CCR-9; chemokine receptor D6; chemokine-binding protein 2; Chemokine-binding protein D6; CMKBR9; D6; D6 beta-chemokine receptor; hD6
• Host Species: Rat
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 1238
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Lyophilized