Invitrogen™ CCR10 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA532695

Product Code. 13424369

Description

Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon (100%); Monkey, Marmoset, Rabbit (94%); Bat, Pig (88%); Rat (82%). For IHC(P), use heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen.

Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC, based on the arrangement of the first 2 of the 4 conserved cysteine residues; the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines. CCR10 is the receptor for CCL27; CCR10-CCL27 interactions are involved in T cell-mediated skin inflammation.

Specifications

• Antigen: CCR10
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CCR10
• Gene Alias: CC chemokine receptor 10; C-C chemokine receptor type 10; C-C CKR-10; C-C motif chemokine receptor 10; CC-CKR-10; CCR10; CCR-10; chemokine (C-C motif) receptor 10; chemokine C-C receptor 9; Cmkbr9; G protein-coupled receptor 2; Gpr2; G-protein coupled receptor 2; MGC151420; RP23-281C18.3
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 2826
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin)
• Concentration: 1 mg/mL
• Formulation: PBS with 0.1% sodium azide
• Gene Accession No.: P46092
• Gene Symbols: CCR10
• Immunogen: Synthetic 17 amino acid peptide from N-terminus of human CCR10.
• Quantity: 50 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG