CCR1 Mouse anti-Human, Clone:8E10F9, Abnova™

Mouse monoclonal antibody raised against recombinant human CCR1.

Brand:  Abnova MAB17628.100ug

Product Code. 16094906

Beschreibung

This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p. [provided by RefSeq]

Spezifikation

• Antigen: CCR1
• Classification: Monoclonal
• Conjugate: Unconjugated
• Dilution: ELISA (1:10000)
  Western Blot (1:500-1:2000)
  Immunocytochemistry
  Flow Cytometry (1:200-1:400)
  Immunohistochemistry
  The optimal working dilution should be determined by the end user.
• Gene: CCR1
• Host Species: Mouse
• Quantity: 100 μg
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA, Flow Cytometry, Western Blot
• Clone: 8E10F9
• Description: chemokine (C-C motif) receptor 1
• Formulation: In PBS (0.05% sodium azide)
• Gene Alias: CD191, CKR-1, CKR1, CMKBR1, HM145, MIP1aR, SCYAR1
• Immunogen: Recombinant protein corresponding to amino acid of human CCR1 from E. coli.
• Gene ID (Entrez): 1230
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid