PeproTech CCL23 Polyclonal Antibody, Biotin, PeproTech®, Invitrogen™

Rabbit Polyclonal Antibody

Brand:  PeproTech 500-P124BT-500UG

Product Code. 30054610

Description

AA Sequence of recombinant protein: RVTKDAETEF MMSKLPLENP VLLDRFHATS ADCCISYTPR SIPCSLLESY FETNSECSKP GVIFLTKKGR RFCANPSDKQ VQVCMRMLKL DTRIKTRKN. Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human MIP-3 (CCL23). Anti-Human MIP-3 (CCL23)-specific antibody was purified by affinity chromatography and then biotinylated. Sandwich ELISA: To detect Human MIP-3 (CCL23) by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.25-1.0 μg/mL of this antibody is required. This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Human MIP-3 (CCL23) (500-P124) as a capture antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Human MIP-3 (CCL23). Western Blot: To detect hMIP-3 by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL. Used in conjunction with compatible secondary reagents the detection limit for Recombinant hMIP-3 is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions. 500-P124BT-1MG will be provided as 2 x 500 μg

This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, displays chemotactic activity on resting T lymphocytes and monocytes, lower activity on neutrophils and no activity on activated T lymphocytes. The protein is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. In addition, the product of this gene is a potent agonist of the chemokine (C-C motif) receptor 1. Alternative splicing results in multiple transcript variants that encode different isoforms.

Specifications

• Antigen: CCL23
• Classification: Polyclonal
• Conjugate: Biotin
• Gene: CCL23
• Gene Alias: C6 beta-chemokine; C-C motif chemokine 23; C-C motif chemokine ligand 23; CCL23; CCL23(19-99); CCL23(22-99); CCL23(27-99); CCL23(30-99); chemokine (C-C motif) ligand 23; Ck beta 8-1; CKb8; CKB-8; Ckb-8-1; CK-BETA-8; hmrp-2a; Macrophage inflammatory protein 3; MIP3; MIP-3; MIP-3CK-BETA-8; MPIF1; MPIF-1; MPIF-1Ckb-8-1; Myeloid progenitor inhibitory factor 1; SCYA23; small inducible cytokine subfamily A (Cys-Cys), member 23; Small-inducible cytokine A23
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 6368
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: ELISA, Western Blot
• Concentration: 0.1-1.0 mg/mL
• Formulation: PBS with no preservative
• Gene Accession No.: P55773
• Gene Symbols: CCL23
• Immunogen: E.coli-derived Recombinant Human MIP-3 (CCL23).
• Quantity: 500 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG