PeproTech CCL21 Polyclonal Antibody, Biotin, PeproTech®, Invitrogen™

Product Code.	Quantity	unitSize
17844013	25 μg	25µg
17844393	50 μg	50µg
17894753	2 x 500 μg	1mg
30054471	500 μg	500µg

Product Code. 17844013 Supplier PeproTech Supplier No. 500P109BT25UG

Description

Rabbit Polyclonal Antibody

AA Sequence of recombinant protein: discontinued. Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human Exodus-2 (CCL21). Anti-Human Exodus-2 (CCL21)-specific antibody was purified by affinity chromatography and then biotinylated. Sandwich ELISA: To detect Human Exodus-2 (CCL21) by sandwich ELISA (using 100 μL/well antibody solution) a concentration of 0.25-1.0 μg/mL of this antibody is required. This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti-Human Exodus-2 (CCL21) (500-P109) as a capture antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Human Exodus-2 (CCL21). Western Blot: To detect hExodus-2 by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 μg/mL. Used in conjunction with compatible secondary reagents the detection limit for Recombinant hExodus-2 is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions. 500-P109BT-1MG will be provided as 2 x 500 μg

This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. Similar to other chemokines the protein encoded by this gene inhibits hemopoiesis and stimulates chemotaxis. This protein is chemotactic in vitro for thymocytes and activated T cells, but not for B cells, macrophages, or neutrophils. The cytokine encoded by this gene may also play a role in mediating homing of lymphocytes to secondary lymphoid organs. It is a high affinity functional ligand for chemokine receptor 7 (CCR7) that is expressed on T and B lymphocytes and a known receptor for another member of the cytokine family (small inducible cytokine A19).

Specifications

• Antigen: CCL21
• Applications: ELISA, Western Blot
• Classification: Polyclonal
• Concentration: 0.1-1.0 mg/mL
• Conjugate: Biotin
• Formulation: PBS with no preservative
• Gene: CCL21
• Gene Accession No.: O00585
• Gene Alias: 6 Ckine; 6CKBAC1; 6CKBAC2; 6Ckine; AI159701; ALP; AW987545; beta chemokine exodus-2; beta-chemokine exodus-2; CC chemokine 6Ckine-ser; C-C motif chemokine 21; C-C motif chemokine 21a; C-C motif chemokine 21b; C-C motif chemokine 21c; C-C motif chemokine ligand 21; CCL21; Ccl21a; Ccl21b; Ccl21c; Ccl21-leu; CCL21-Ser; chemokine (C-C motif) ligand 21; chemokine (C-C motif) ligand 21A (serine); chemokine (C-C motif) ligand 21B (leucine); chemokine (C-C motif) ligand 21b (serine); chemokine (C-C motif) ligand 21C (leucine); chemokine CCL21/6CKINE; CKb9; ECL; Efficient Chemoattractant for Lymphocytes; exodus-2; plt; Scya21; SCYA21a; Scya21b; Scya21c; secondary lymphoid organ chemokine; secondary lymphoid tissue chemokine; Secondary lymphoid-tissue chemokine; SLC; small inducible cytokine A21; small inducible cytokine A21a; small inducible cytokine A21c; small inducible cytokine subfamily A (Cys-Cys), member 21; small-inducible cytokine A21; Small-inducible cytokine A21a; Small-inducible cytokine A21b; Small-inducible cytokine A21c; TCA4; Thymus-derived chemotactic agent 4; UNQ784/PRO1600
• Gene Symbols: CCL21
• Host Species: Rabbit
• Immunogen: E.coli-derived Recombinant Human Exodus-2 (CCL21).
• Purification Method: Antigen affinity chromatography
• Quantity: 25 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 6366
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Lyophilized