CCDC99 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Product Code	Brand	Quantity
16863175	Proteintech 24689-1-AP-20UL	20 μL
16853175	Proteintech 24689-1-AP-150UL	150 μL

Description

The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Differential and in situ hybridizations indicate that this lectin is specifically expressed in keratinocytes. It is expressed at all stages of epidermal differentiation (i.e., in basal and suprabasal layers). The protein was found mainly in stratified squamous epithelium. It is moderately repressed by retinoic acid. The antigen localized to basal keratinocytes, although it was also found at lower levels in the suprabasal layers, where it concentrated to areas of cell-to-cell contact. The cellular localization and its striking down-regulation in cultured keratinocytes imply a role in cell-cell and/or cell-matrix interactions necessary for normal growth control.

Specifications

• Antigen: CCDC99
• Applications: Immunoprecipitation, Immunohistochemistry (Paraffin), Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human
• Gene Accession No.: Q96EA4
• Gene ID (Entrez): 54908
• Immunogen: CCDC99 Fusion Protein Ag20430
• Primary or Secondary: Primary
• Content And Storage: -20°C
• Gene: SPDL1

• Concentration: 0.28 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Alias: CCDC99, hSpindly, MU-RMS-40.4A, Protein Spindly, spdly
• Gene Symbols: SPDL1
• Isotype: IgG
• Purification Method: Antigen Affinity Chromatography
• Product Type: Antibody