Invitrogen™ CCDC67 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA552768

Product Code. 15710721

Description

Immunogen sequence: MKQNKVPRKE LPHLKEEIPF ELSNLNQKLE EFRAKSREWD KQEILYQTHL ISLDAQQKLL SEKCNQFQKQ AQSYQTQLNG KKQCLEDSSS EIPRLICDPD PNCEINERDE FIIEKLKSAV NEIALSRNKL QD Highest antigen sequence identity to the following orthologs: Mouse - 83%, Rat - 80%.

CCDC67 (deuterosome assembly protein 1) is a key structural component of the deuterosome, a structure that promotes de novo centriole amplification in multiciliated cells. Deuterosome-mediated centriole amplification occurs in terminally differentiated multiciliated cells and can generate more than 100 centrioles. Probably sufficient for the specification and formation of the deuterosome inner core. The protein interacts with CEP152 and recruits PLK4 to activate centriole biogenesis.

Specifications

• Antigen: CCDC67
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Deup1
• Gene Alias: 4933401K09Rik; CCDC67; coiled-coil domain containing 67; coiled-coil domain-containing protein 67; Deup1; deuterosomal protein 1; deuterosome assembly protein 1; deuterosome protein 1; RGD1306632
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 159989
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.2 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q05D60
• Gene Symbols: Deup1
• Immunogen: Recombinant protein corresponding to Human CCDC67. Recombinant protein control fragment (Product #RP-90402).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG