Invitrogen™ CCDC53 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5100429

Product Code. 16626914

Description

Antibody detects endogenous levels of total CCDC53.

Acts as a component of the WASH core complex that functions as a nucleation-promoting factor (NPF) at the surface of endosomes, where it recruits and activates the Arp2/3 complex to induce actin polymerization, playing a key role in the fission of tubules that serve as transport intermediates during endosome sorting. [UniProt].

Specifications

• Antigen: CCDC53
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: WASHC3
• Gene Alias: 2900091E11Rik; 5730495F03Rik; AD-016; Ccdc53; CGI-116; coiled-coil domain containing 53; coiled-coil domain-containing protein 53; RGD1563761; WASH complex subunit 3; WASH complex subunit CCDC53; WASHC3; x0009
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 299707, 51019, 67282
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: Q9CR27, Q9Y3C0
• Gene Symbols: WASHC3
• Immunogen: A synthesized peptide derived from human WASHC3(Accession Q9Y3C0), corresponding to amino acid residues V143-S193.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG