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Invitrogen™ CCDC134 Polyclonal Antibody
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Product Code. 12878922
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Quantity:
100 μg
Unit Size:
100µg
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12878922 100 μg 100µg
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Product Code. 12878922 Supplier Invitrogen™ Supplier No. PA520780

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Description

Rabbit Polyclonal Antibody

A suggested positive control is rat brain tissue lysate. PA5-20780 can be used with blocking peptide PEP-0894.

The coiled-coil domain is a common protein motif that is often involved in protein oligomerization and is found in proteins such as transcription factors and intermediate filaments. One such protein is CCDC134, a recently identified secretory protein that has been found to inhibit the transcriptional activity of the Elk1 protein. Overexpression CCDC134 also inhibited the phosphorylation of Erk and JNK/SAPK but not p38 MAPK, while specific siRNA against CCDC134 activated Elk1 transcriptional activity and the phosphorylation of Erk and JNK/SAPK, suggesting a potential inhibiting role of CCDC134 in MAPK-mediated Elk1 transcription. CCDC134 is widely expressing in normal adult tissues, tumors, and cell lines.
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Specifications

Antigen CCDC134
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene CCDC134
Gene Accession No. Q5M862, Q8C7V8, Q9H6E4
Gene Alias 2310042L06Rik; AW208859; Ccdc134; coiled-coil domain containing 134; coiled-coil domain-containing protein 134; dJ821D11.3
Gene Symbols CCDC134
Host Species Rabbit
Immunogen A 17 amino acid peptide near the amino terminus of human CCDC134.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 500909, 76457, 79879
Target Species Human, Mouse, Rat
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG
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