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Invitrogen™ CCDC106 Polyclonal Antibody

Product Code. 12819152
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Quantity:
100 μg
Unit Size:
100µg
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Product Code. Quantity unitSize
12819152 100 μg 100µg
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Product Code. 12819152 Supplier Invitrogen™ Supplier No. PA521003

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Description

Rabbit Polyclonal Antibody

A suggested positive control is human brain tissue lysate. PA5-21003 can be used with blocking peptide PEP-1117.

The coiled-coil domain is a common protein motif that is often involved in protein oligomerization and is found in proteins such as transcription factors and intermediate filaments. CCDC106 was initially identified as a p53-interacting protein by yeast two-hybrid screening. Other experiments demonstrated that CCDC106 co-localizes and interacts with p53 in the nucleus, inhibiting the transcriptional activity of p53 and stimulating p53 protein degradation, indicating that at least one of the functions of CCDC106 is acting as a negative regulator of p53.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CCDC106
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene CCDC106
Gene Accession No. Q3ULM0, Q9BWC9
Gene Alias BC018462; CCDC106; coiled-coil domain containing 106; coiled-coil domain-containing protein 106; HSU79303; MNCb-2071; protein predicted by clone 23882; RGD1566222; ZNF581
Gene Symbols CCDC106
Host Species Rabbit
Immunogen A 15 amino acid peptide near the carboxy terminus of human CCDC106.
Purification Method Antigen Affinity Chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 232821, 29903, 499071
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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