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Tocris Bioscience™ CC 401 dihydrochloride

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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
Description
High affinity JNK inhibitor (Ki values are 25-50 nM). Inhibits JNK via competitive binding of the ATP-binding site of active, phosphorylated JNK. Exhibits > 40-fold selectivity for JNK over p38, ERK, IKK2, protein kinase C, Lck and ZAP70. Hepatoprotective. Also inhibits HCMV replication.
Specifications
Specifications
| Quantity | 10 mg |
| Solubility | Soluble to 100mM in water and to 100mM in DMSO |
| Formula Weight | 461.39 |
| Physical Form | Solid |
| Purity | >98% |
| Chemical Name or Material | 3-[3-[2-(1-Piperidinyl)ethoxy]phenyl]-5-(1H-1,2,4-triazol-5-yl)-1H-indazole dihydrochloride |
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