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  6. Invitrogen™ CBX4 Recombinant Rabbit Monoclonal Antibody (K01_2K70)

Invitrogen™ CBX4 Recombinant Rabbit Monoclonal Antibody (K01_2K70)

Product Code. 30830319
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Quantity:
50 μL
100 μL
Unit Size:
50µL
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30830319 50 μL 50µL
30827872 100 μL -
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Product Code. 30830319 Supplier Invitrogen™ Supplier No. MA565424
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Description

Rabbit Recombinant Monoclonal Antibody

Immunogen sequence: TAEKPPAEAQ DEPA.

Polycomb group (PcG) proteins are chromatin-associated proteins which are important for embryonic and adult stem cell self-renewal and maintenance. At least two distinct human PcG complexes have been identified. Polycomb repressive complex I (PRC1) contains CBX4/Pc2, HPH1 and RING domain-containing proteins (RING1, RING2 and BMI1). CBX4 (Chromobox protein homolog 4 or PC2), which functions as a transcriptional suppressor, is a candidate of KyoT2-binding proteins. It is a E3 SUMO-protein ligase which facilitates SUMO1 conjugation. Depletion of CBX4 results in decreased cellular resistance to ionizing radiation. CBX4 is directly involved in the cellular response to DNA damage.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CBX4
Applications Western Blot
Classification Recombinant Monoclonal
Clone K01_2K70
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 50mM tris glycine with 0.05% BSA, 40% glycerol, 150mM NaCl and 0.01% sodium azide; pH 7.4
Gene CBX4
Gene Accession No. O00257, O55187
Gene Alias Cbx4; chromobox 4; chromobox homolog 4; chromobox homolog 4 (Pc class homolog, Drosophila); chromobox protein homolog 4; chromobox-like protein 4; E3 SUMO-protein ligase CBX4; E3 SUMO-protein transferase CBX4; hPc2; MPc2; NBP16; NS5ATP1-binding protein 16; Pc class 2 homolog; PC2; Polycomb 2 homolog
Gene Symbols CBX4
Host Species Rabbit
Immunogen A synthetic peptide of human CBX4 (aa 514-527).
Purification Method Protein A/G
Quantity 50 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12418, 501403, 8535
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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