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  6. CBP/EIF4E Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

CBP/EIF4E Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Product Code. 16828033 Shop All Proteintech Products
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150 μL
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16828033 20 μL 20µL
16818033 150 μL 150µL
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Product Code. 16828033 Supplier Proteintech Supplier No. 111491AP20UL

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Description

Rabbit Polyclonal Antibody

This is a rabbit polyclonal antibody raised against the full-length human EIF4E protein. This protein can form a dimer (∽50 kDa).

eIF4E is involved in several cellular processes including enhanced translational efficiency, splicing, mRNA stability, and RNA nuclear export. All eukaryotic cellular mRNAs are blocked at their 5-prime ends with the 7-methylguanosine cap structure, m7GpppX (where X is any nucleotide). EIF4E is a eukaryotic translation initiation factor involved in directing ribosomes to the cap structure of mRNAs. It is a 24-kD polypeptide that exists as both a free form and as part of a multiprotein complex termed EIF4F. The EIF4E polypeptide is the rate-limiting component of the eukaryotic translation apparatus and is involved in the mRNA-ribosome binding step of eukaryotic protein synthesis. The other subunits of EIF4F are a 50-kD polypeptide, termed EIF4A, that possesses ATPase and RNA helicase activities, and a 220-kD polypeptide, EIF4G.

Specifications

Antigen CBP/EIF4E
Applications Immunohistochemistry (Paraffin), Immunocytochemistry, Western Blot, Immunofluorescence, Flow Cytometry
Classification Polyclonal
Concentration 0.17 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Gene EIF4E
Gene Accession No. P06730, P63073, P63074
Gene Alias CBP, eIF 4E, eIF 4F 25 kDa subunit, EIF4E, EIF4E1, EIF4EL1, EIF4F, mRNA cap binding protein
Gene Symbols Eif4e
Host Species Rabbit
Immunogen CBP,EIF4E Fusion Protein Ag1626
Purification Method Antigen Affinity Chromatography
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 117045, 13684, 1977
Target Species Rat, Mouse, Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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