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Invitrogen™ Caveolin 2 Recombinant Rabbit Monoclonal Antibody (K01_1N98)
Description
Caveolin 2 Recombinant Monoclonal Antibody for ICC/IF, IHC (P), Western Blot
Caveolae are specialized domains of the plasma membrane that are implicated in the sequestration of a variety of lipid and protein molecules. It has been suggested that these important cellular organelles have a pivotal role in such diverse biochemical processes as lipid metabolism, growth regulation, signal transduction, and apoptosis. Caveolin interacts with and regulates heterotrimeric G-proteins. Currently, there are three members of the caveolin multigene family which are known to encode 21-24 kDa integral membrane proteins that comprise the major structural component of the caveolar membrane in vivo. Caveolin-2 protein is abundantly expressed in fibroblasts and differentiated adipocytes, smooth and skeletal muscle, and endothelial cells. The expression of caveolin-1 is similar to that of caveolin-2 while caveolin-3 expression appears to be limited to muscle tissue types.
Specifications
Specifications
| Antigen | Caveolin 2 |
| Applications | Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry |
| Classification | Recombinant Monoclonal |
| Clone | K01_1N98 |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | 50mM tris glycine with 40% glycerol, 150mM NaCl, 0.05% BSA and 0.01% sodium azide; pH 7.4 |
| Gene | CAV2 |
| Gene Accession No. | P51636 |
| Gene Alias | AI447843; CAV; CAV2; caveolae; caveolae protein, 20-kD; caveolin 2; caveolin 2 isoform a and b; caveolin-2; MGC12294; Phospho-CAV2 |
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