Invitrogen™ Caveolin 1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA517447

Product Code. 11506271

Description

It is not recommended to aliquot this antibody. This antibody is not cross-reactive with caveolin-2 or -3.

Caveolin-1 or CAV1 is a scaffolding proteins within caveolar membranes. It interacts directly with G-protein alpha subunits and can functionally regulate their activity. Caveolin-1 is also involved in the co-stimulatory signal essential for T-cell receptor (TCR) mediated T-cell activation. It can bind with DPP4 and induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Mutations affecting the CAV1 gene can result in congenital generalized lipodystrophy 3, pulmonary hypertension primary 3, or partial lipodystrophy/congenital cataracts, and neurodegeneration syndrome.

Specifications

• Antigen: Caveolin 1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CAV1
• Gene Alias: BSCL3; CAV; CAV1; Cav-1; caveolae; caveolin 1; caveolin 1, caveolae protein; caveolin 1, caveolae protein, 22kDa; caveolin 1a; caveolin 1b; caveolin caveolae protein 22 kDa; caveolin, caveolae protein 1; caveolin, caveolae protein, 22 kDa; caveolin-1; caveolin-1a; caveolin-1b; cell growth-inhibiting protein 32; CGL3; HGNC:1527; LCCNS; MSTP085; OTTHUMP00000196475; PPH3; Unknown (protein for IMAGE:7985573); variant a; variant b; vesicular integral-membrane protein VIP21; VIP21; wu:fc07c04
• Host Species: Rabbit
• Purification Method: Protein A, Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 100753021, 12389, 25404, 281040, 323695, 373996, 404693, 857
• Content And Storage: -20°C
• Form: Liquid

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
• Concentration: 33 μg/mL
• Formulation: 0.01M HEPES with 100μg/mL BSA, 50% glycerol, 0.15M NaCl and no preservative; pH 7.5
• Gene Accession No.: P35431, P41350, P49817, P79132, Q03135, Q6RVA9
• Gene Symbols: CAV1
• Immunogen: Synthetic peptide corresponding to residues surrounding Glu20 of human caveolin-1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Bovine, Chicken, Hamster, Human, Mouse, Pig, Rat, Zebrafish
• Product Type: Antibody
• Isotype: IgG