Invitrogen™ CaV1.3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA5120487

Product Code. 17771884

Description

Positive test controls include: Rat kidney. The target is usually found in the following locations: Membrane, Multi-pass membrane protein. Immunogen sequence: RQNYGYYSRY PGRNIDSERP RGYHHPQGFL EDDDSPVCYD SRRSPRRRLL PPTPASHRRS SFNFECLRRQ SSQEEVPSSP IFPHRTALPL HLMQQQIMAV AGLDSSKAQK YSPSHSTRSW ATPPATPPYR DWTPCYTPLI QVEQSEALDQ VNGSLPSLHR SSWYTDEPDI SYRTFTPASL TVPSSFRNKN SDKQRSADSL VEAVLISEGL GRYARDPKFV SATKHEIADA CDLTIDEMES AASTLLNGNV RPRANGDVGP LSHRQDYELQ DFGPGYSDEE PDPGRDEEDL ADEMICITTL.

CACNA1D is also known as PASNA, SANDD or Cav1. 3. Voltage-dependent calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, and gene expression. Calcium channels are multisubunit complexes composed of alpha-1, beta, alpha-2/delta, and gamma subunits. The channel activity is directed by the pore-forming alpha-1 subunit, whereas the others act as auxiliary subunits regulating this activity. The distinctive properties of the calcium channel types are related primarily to the expression of a variety of alpha-1 isoforms, namely alpha-1A, B, C, D, E, and S. This gene encodes the alpha-1D subunit. Several transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: CaV1.3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CACNA1D
• Gene Alias: 8430418G19Rik; brain class D; C79217; Cach3; Cacn4; CACNA 1D; CACNA1D; Cacnl1a2; calcium channel alpha-1 subunit; Calcium channel, L type, alpha-1 polypeptide isoform 2; Calcium channel, L type, alpha-1 polypeptide, isoform 2; calcium channel, neuroendocrine/brain-type, alpha 1 subunit; calcium channel, voltage-dependent, L type, alpha 1D subunit; calcium voltage-gated channel subunit alpha1 D; Cav1.3; CaV1.3alpha1; Cchl1a; CCHL1A2; D-LTCC; PASNA; Rat brain class D; RBD; SANDD; voltage-dependent calcium channel subunit alpha1D; voltage-dependent L-type calcium channel subunit alpha-1D; voltage-gated calcium channel alpha 1 subunit; voltage-gated calcium channel alpha subunit Cav1.3; voltage-gated calcium channel pore forming subunit CaV1.3alpha1 IVS3-IVS4 extracellular linker; voltage-gated calcium channel subunit alpha Cav1.3
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 29716, 776
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1.82 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: P27732, Q01668
• Gene Symbols: CACNA1D
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1882-2181 of human CACNA1D (NP_000711.1).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG