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  6. Invitrogen™ Cathepsin O Recombinant Mouse Monoclonal Antibody (K06376_14F12)

Invitrogen™ Cathepsin O Recombinant Mouse Monoclonal Antibody (K06376_14F12)

Product Code. 30828543
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30825068 50 μL
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Product Code. 30828543 Supplier Invitrogen™ Supplier No. MA564491

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Description

Mouse Recombinant Monoclonal Antibody

Immunogen sequence: VESAYAIKGK PLEDLSVQQV IDCSYNNYGC NGGSTLNALN WLNKMQVKLV KDSEYPFKAQ NGLCHYFSGS HSGFSIKGYS AYDFSDQEDE Highest antigen sequence identity to the following orthologs: Mouse - 66%, Rat - 37%, Pig - 88%, Cynomolgus monkey - 98%.

The cathepsin family of proteolytic enzymes contains several diverse classes of proteases. The cysteine protease class comprises cathepsins B, L, H, K, S, and O. The aspartyl protease class is composed of cathepsins D and E. Cathepsin G is in the serine protease class. Most cathepsins are lysosomal and each is involved in cellular metabolism, participating in various events such as peptide biosynthesis and protein degradation. Cathepsin O maintains the structural features characteristic of other cysteine proteinases including the active site cysteine residue that is involved in covalent intermediate formation during peptide hydrolysis. Cathepsin O is an endoproteinase that may be involved in extracellular matrix degradation. Cathepsin O is abundantly expressed in the ovary, kidney and placenta with lower levels found in thymus and skeletal muscle.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Cathepsin O
Applications Immunohistochemistry (Paraffin)
Classification Recombinant Monoclonal
Clone K06376_14F12
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol, 0.5% BSA and 0.09% sodium azide
Gene CTSO
Gene Accession No. P43234
Gene Alias A330105D01Rik; A430056C07; AI118514; cathepsin O; Ctso; CTSO1; LOC684529; similar to cathepsin O
Gene Symbols CTSO
Host Species Mouse
Immunogen Recombinant human CTSO (aa 141-230).
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1519
Target Species Human
Content And Storage Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG2a
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