Invitrogen™ Cathepsin O Monoclonal Antibody (180406)

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA560933

Product Code. 30534225

Description

Reconstitute at 0.5 mg/mL in sterile PBS.

The cathepsin family of proteolytic enzymes contains several diverse classes of proteases. The cysteine protease class comprises cathepsins B, L, H, K, S, and O. The aspartyl protease class is composed of cathepsins D and E. Cathepsin G is in the serine protease class. Most cathepsins are lysosomal and each is involved in cellular metabolism, participating in various events such as peptide biosynthesis and protein degradation. Cathepsin O maintains the structural features characteristic of other cysteine proteinases including the active site cysteine residue that is involved in covalent intermediate formation during peptide hydrolysis. Cathepsin O is an endoproteinase that may be involved in extracellular matrix degradation. Cathepsin O is abundantly expressed in the ovary, kidney and placenta with lower levels found in thymus and skeletal muscle.

Specifications

• Antigen: Cathepsin O
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with trehalose and no preservative
• Gene Accession No.: P43234
• Gene Symbols: CTSO
• Immunogen: Mouse myeloma cell line NS0-derived recombinant human Cathepsin O, Asp24-Val321.
• Quantity: 500 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Immunoprecipitation, Western Blot
• Clone: 180406
• Conjugate: Unconjugated
• Gene: CTSO
• Gene Alias: A330105D01Rik; A430056C07; AI118514; cathepsin O; Ctso; CTSO1; LOC684529; similar to cathepsin O
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 1519
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Lyophilized