Invitrogen™ Cathepsin H Polyclonal Antibody

Goat Polyclonal Antibody

Brand:  Invitrogen™ PA547041

Product Code. 15557532

Description

In direct ELISAs and Western blots, approximately 25% cross-reactivity with recombinant human (rh) Cathepsin H is observed and less than 2% cross-reactivity with recombinant mouse (rm) Cathepsin B, rmCathepsin C, rmCathepsin Z, rmCathepsin L, and rhCathepsin O is observed. Reconstitute at 0.2 mg/mL in sterile PBS.

The cathepsin family of proteolytic enzymes contains several diverse classes of proteases. The cysteine protease class comprises cathepsins B, L, H, K, S, and O. The aspartyl protease class is composed of cathepsins D and E. Cathepsin G is in the serine protease class. Most cathepsins are lysosomal and each is involved in various cellular events such as peptide biosynthesis and protein degradation. The propeptide region of cathepsin H is highly homologous to other cathepsins. This region is thought to play a role in the processing of cysteine proteases. Cathepsin H is thought to be involved in several pathological conditions, including neuro degenerative disorders and cancer.

Specifications

• Antigen: Cathepsin H
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CTSH
• Gene Alias: ACC4; ACC-4; ACC5; ACC-5; AL022844; aleurain; Cat H; CATH; cathepsin B3; Cathepsin BA; cathepsin H; Cathepsin H heavy chain; Cathepsin H light chain; Cathepsin H mini chain; CPSB; Ctsh; N-benzoylarginine-beta-naphthylamide hydrolase; pro-cathepsin H
• Host Species: Goat
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 13036
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot
• Concentration: 0.2 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: P49935
• Gene Symbols: CTSH
• Immunogen: Mouse myeloma cell line NS0-derived recombinant mouse Cathepsin H Glu22-Val333.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG