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Invitrogen™ Cathelicidin Polyclonal Antibody

Product Code. 12838692
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Quantity:
100 μg
Unit Size:
100µg
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12838692 100 μg 100µg
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Product Code. 12838692 Supplier Invitrogen™ Supplier No. PA520513

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Description

Rabbit Polyclonal Antibody

A suggested positive control is human spleen tissue lysate. PA5-20513 can be used with blocking peptide PEP-0633. The immunogen is located within amino acids 50 - 100 of Cathelicidin.

Cathelicidin is an epithelial-derived antimicrobial protein found in specific granules of polymorphonuclear leukocytes of bone marrow, testis and neutrophils. Cathelicidins are one family of antimicrobial peptides characterized by conserved pro-peptide sequences that have been identified in epithelial tissues and some myeloid cells of humans and animals. LL-37/hCAP-18 is the only Cathelicidin found in humans and is expressed in inflammatory and epithelial cells. The presence of these molecules is essential for defense against invasive bacterial infection in skin. Besides their direct antimicrobial function, Cathelicidins have multiple roles in mediating innate and adaptive immunity, such as endotoxin neutralizing, angiogenesis, wound healing and promoting neutrophil chemotaxis and mast cell recruitment. Cathelicidin antimicrobial peptides qualify as prototypes of innovative drugs that may be used to treat infection and/or modulate the immune response.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Cathelicidin
Applications Immunohistochemistry, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene CAMP
Gene Accession No. P49913
Gene Alias 18 kDa cationic antimicrobial protein; Antibacterial peptide FALL-39; Antibacterial peptide LL-37; Camp; CAP18; CAP-18; Cathelicidin antimicrobial peptide; cathelin-like protein; Cathelin-related antimicrobial peptide; CLP; Cnlp; CRAMP; FALL39; FALL-39; FALL-39 peptide antibiotic; hCAP18; hCAP-18; HSD26; LL37; MCLP
Gene Symbols CAMP
Host Species Rabbit
Immunogen A 17 amino acid synthetic peptide near the center of the human Cathelicidin.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 820
Target Species Human
Content And Storage 4°C, do not freeze
Product Type Antibody
Form Liquid
Isotype IgG
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