Invitrogen™ Cathelicidin Polyclonal Antibody

Goat Polyclonal Antibody

Brand:  Invitrogen™ PA5142372

Product Code. 17807122

Description

This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:2,000.

Cathelicidin is an epithelial-derived antimicrobial protein found in specific granules of polymorphonuclear leukocytes of bone marrow, testis and neutrophils. Cathelicidins are one family of antimicrobial peptides characterized by conserved pro-peptide sequences that have been identified in epithelial tissues and some myeloid cells of humans and animals. LL-37/hCAP-18 is the only Cathelicidin found in humans and is expressed in inflammatory and epithelial cells. The presence of these molecules is essential for defense against invasive bacterial infection in skin. Besides their direct antimicrobial function, Cathelicidins have multiple roles in mediating innate and adaptive immunity, such as endotoxin neutralizing, angiogenesis, wound healing and promoting neutrophil chemotaxis and mast cell recruitment. Cathelicidin antimicrobial peptides qualify as prototypes of innovative drugs that may be used to treat infection and/or modulate the immune response.

Specifications

• Antigen: Cathelicidin
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CAMP
• Gene Alias: 18 kDa cationic antimicrobial protein; Antibacterial peptide FALL-39; Antibacterial peptide LL-37; Camp; CAP18; CAP-18; Cathelicidin antimicrobial peptide; cathelin-like protein; Cathelin-related antimicrobial peptide; CLP; Cnlp; CRAMP; FALL39; FALL-39; FALL-39 peptide antibiotic; hCAP18; hCAP-18; HSD26; LL37; MCLP
• Host Species: Goat
• Purification Method: Ammonium sulfate precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 820
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P49913
• Gene Symbols: CAMP
• Immunogen: Peptide with sequence KETVCPRTTQQSP.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG