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  6. Invitrogen™ Catenin alpha-1 Recombinant Rabbit Monoclonal Antibody (K01_1M61)

Invitrogen™ Catenin alpha-1 Recombinant Rabbit Monoclonal Antibody (K01_1M61)

Product Code. 30829689
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30829689 50 μL
30826192 100 μL
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Product Code. 30829689 Supplier Invitrogen™ Supplier No. MA564734
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Estimated Shipment: 09-11-2026
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Description

Rabbit Recombinant Monoclonal Antibody

Catenin alpha-1 Recombinant Monoclonal Antibody for Western Blot

Associates with the cytoplasmic domain of a variety of cadherins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties. Can associate with both E- and N-cadherins. Originally believed to be a stable component of E-cadherin/catenin adhesion complexes and to mediate the linkage of cadherins to the actin cytoskeleton at adherens junctions. In contrast, cortical actin was found to be much more dynamic than E-cadherin/catenin complexes and CTNNA1 was shown not to bind to F-actin when assembled in the complex suggesting a different linkage between actin and adherence junctions components. The homodimeric form may regulate actin filament assembly and inhibit actin branching by competing with the Arp2/3 complex for binding to actin filaments. May play a crucial role in cell differentiation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Catenin alpha-1
Applications Western Blot
Classification Recombinant Monoclonal
Clone K01_1M61
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation 50mM tris glycine with 0.05% BSA, 150mM NaCl, 40% glycerol and 0.01% sodium azide; pH 7.4
Gene CTNNA1
Gene Accession No. P26231, P35221
Gene Alias [a]E-catenin; 102 kDa cadherin-associated protein; 2010010M04Rik; AA517462; AI988031; alpha E catenin; alpha E-catenin; alpha(E)-catenin; alpha-E-catenin; cadherin associated protein; Cadherin-associated protein; CAP102; catenin (cadherin associated protein), alpha 1; catenin (cadherin-associated protein), alpha; catenin (cadherin-associated protein), alpha 1; catenin (cadherin-associated protein), alpha 1, 102kDa; catenin alpha 1; catenin alpha 1 S homeolog; catenin alpha-1; catenin, alpha 1; Catna1; cell-adhesion protein alphaE catenin; ctnna; ctnna1; ctnna1.S; MDPT2; Renal carcinoma antigen NY-REN-13; XELAEV_18020018mg
Gene Symbols CTNNA1
Host Species Rabbit
Immunogen A synthetic peptide of human alpha 1 Catenin.
Purification Method Protein A/G
Quantity 50 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12385, 1495, 307505
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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