Caspase 9/p35/p10 Mouse anti-Human, Mouse, Clone: 1B7G2, Proteintech

Mouse Monoclonal Antibody

Brand:  Proteintech 66169-1-IG-20UL

Product Code. 16897795

Description

Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates caspase-3. Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP).

Specifications

• Antigen: Caspase 9/p35/p10
• Classification: Monoclonal
• Concentration: 1.5 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P55211, Q8C3Q9
• Gene Symbols: CASP9
• Immunogen: Caspase 9/p35/p10 Fusion Protein Ag20813
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Mouse, Human
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Clone: 1B7G2
• Conjugate: Unconjugated
• Gene: CASP9
• Gene Alias: APAF 3, APAF3, Apoptotic protease Mch 6, CASP 9, CASP9, Caspase 9, Caspase 9/p35/p10, CASPASE 9c, Caspase9, Caspase-9, ICE LAP6, ICE like apoptotic protease 6, MCH6
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 12371, 842
• Content And Storage: -20°C
• Form: Liquid