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Caspase 10 Polyclonal Antibody, Invitrogen™

Product Code. 11525992
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Quantity:
100 μg
Unit Size:
100µg
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11525992 100 μg 100µg
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Product Code. 11525992 Supplier Invitrogen Supplier No. PA112507

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Rabbit Polyclonal Antibody

A suggested positive control for this product is HeLa whole cell lysate.

Caspases are cysteine proteases, expressed as inactive precursors, that mediate apoptosis by proteolysis of specific substrates. Caspases have the ability to cleave after aspartic acid residues. There are two classes of caspases involved in apoptosis; initiators (activation by receptor cluster) and effectors (activation by mitochondrial permeability transition). Proapoptotic signals autocatalytically activate initiator caspases, such as Caspase-8 and Caspase 9. Activated initiator caspases then process effector caspases, such as Caspase-3 and Caspase-7, which in turn cause cell collapse.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Caspase 10
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene CASP10
Gene Accession No. Q92851
Gene Alias ALPS2, FLICE2, MCH4
Gene Symbols CASP10
Host Species Rabbit
Immunogen Synthetic peptide corresponding to residues 505-521 of human FLICE2.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 843
Target Species Human, Mouse, Rat
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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