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Caspase 1 Recombinant Rabbit Monoclonal Antibody (HL2005), Invitrogen™
Rabbit Recombinant Monoclonal Antibody
Brand: Invitrogen MA547253
This item is not returnable.
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Description
Store as concentrated solution. Centrifuge briefly prior to opening vial.
Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. Members of this subfamily include caspase-1, -4, -5, and -12 and can activate proinflammatory cytokines such as IL-1-b and IL-18. Caspase-1 was initially identified as an IL-1-b-converting enzyme; later experiments revealed it to be a mammalian homolog of the C. elegans cell death gene ced-3 whose overexpression can induce apoptosis in fibroblasts.
Specifications
| Caspase 1 | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with no preservative | |
| P29466 | |
| CASP1 | |
| Recombinant fragment of human Caspase 1 | |
| 100 μL | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
| Western Blot | |
| HL2005 | |
| Unconjugated | |
| CASP1 | |
| CASP1; CASP-1; CASP1 nirs variant 1; caspase 1; caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase); Caspase1; caspase-1; Caspase-1 subunit p10; Caspase-1 subunit p20; ICE; IL-1 beta-converting enzyme; IL-1B converting enzyme; IL1BC; IL-1BC; IL1BCE; IL1B-convertase; interleukin 1 beta-converting enzyme; interleukin 1, beta, convertase; interleukin 1-B converting enzyme; Interleukin 1beta converting enzyme; interleukin-1 beta convertase; Interleukin-1 beta-converting enzyme; p45 | |
| Rabbit | |
| Protein A | |
| RUO | |
| 834 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |