Invitrogen™ CARS Monoclonal Antibody (CL2310)

Mouse Monoclonal Antibody

Brand:  Invitrogen™ MA524637

Product Code. 15729290

Description

Immunogen sequence: SQCNLYMAAR KAVRKRPNQA LLENIALYLT HMLKIFGAVE EDSSLGFPVG GPGTSLSLEA TVMPYLQVLS EFREGVRKIA REQKVPEILQ LSDALRDNIL PELGVRFEDH EGLPTVVKLV DRNTLLKERE EKRRVE Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 86%. Binds to an epitope located within the peptide sequence EDSSLGFPVG as determined by overlapping synthetic peptides.

This gene encodes a class 1 aminoacyl-tRNA synthetase, cysteinyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. This gene is one of several located near the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.

Specifications

• Antigen: CARS
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: P49589
• Gene Symbols: CARS, CARS1
• Immunogen: Recombinant protein fragment of Human CARS (Product #RP-101867)
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: CL2310
• Conjugate: Unconjugated
• Gene: CARS1
• Gene Alias: CA3; CARS; cars protein; CARS1; CYSRS; cysteine translase; cysteine tRNA ligase 1, cytoplasmic; cysteine--tRNA ligase, cytoplasmic; Cysteinyl-tRNA synthetase; cysteinyl-tRNA synthetase 1; cysteinyl-tRNA synthetase, cytoplasmic; LOW QUALITY PROTEIN: cysteine--tRNA ligase, cytoplasmic; MGC:11246; sb:cb71
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 833
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid