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Invitrogen™ CARD11 Polyclonal Antibody
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Product Code. 11376113
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Quantity:
100 μg
Unit Size:
100µg
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11376113 100 μg 100µg
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Product Code. 11376113 Supplier Invitrogen™ Supplier No. PA518145

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Description

Goat Polyclonal Antibody

This antibody is predicted to react with bovine, canine and mouse based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000.

The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CARD11
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene CARD11
Gene Accession No. Q9BXL7
Gene Alias 0610008L17Rik; 2410011D02Rik; bcl10-interacting maguk protein 3; BENTA; BIMP3; Card11; CARD-containing MAGUK protein 1; Carma 1; CARMA1; caspase recruitment domain family member 11; caspase recruitment domain family, member 11; caspase recruitment domain-containing protein 11; IMD11; LOC100363332; MGC133069; PPBL
Gene Symbols CARD11
Host Species Goat
Immunogen Synthetic peptide sequence (QRKTIWVDEDQL) corresponding to the C-terminus amino acids of CARD11 (aa 1143-1154).
Purification Method Ammonium Sulfate Precipitation
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 84433
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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