Invitrogen™ CARD11 Polyclonal Antibody

Goat Polyclonal Antibody

Brand:  Invitrogen™ PA518145

Product Code. 11376113

Description

This antibody is predicted to react with bovine, canine and mouse based on sequence homology. This antibody is tested in Peptide ELISA: antibody detection limit dilution 32,000.

The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10.

Specifications

• Antigen: CARD11
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CARD11
• Gene Alias: 0610008L17Rik; 2410011D02Rik; bcl10-interacting maguk protein 3; BENTA; BIMP3; Card11; CARD-containing MAGUK protein 1; Carma 1; CARMA1; caspase recruitment domain family member 11; caspase recruitment domain family, member 11; caspase recruitment domain-containing protein 11; IMD11; LOC100363332; MGC133069; PPBL
• Host Species: Goat
• Purification Method: Ammonium Sulfate Precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 84433
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q9BXL7
• Gene Symbols: CARD11
• Immunogen: Synthetic peptide sequence (QRKTIWVDEDQL) corresponding to the C-terminus amino acids of CARD11 (aa 1143-1154).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG