Carboxypeptidase B2 Monoclonal Antibody (19E2), Invitrogen™

Mouse Monoclonal Antibody

Brand:  Invitrogen MA125769

Product Code. 11569352

Description

MA1-25769 detects Carboxypeptidase B2 from human samples.

Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). CPB2 is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Polymorphisms have been described for its gene and its promoter region.

Specifications

• Antigen: Carboxypeptidase B2
• Classification: Monoclonal
• Concentration: 4 mg/mL
• Formulation: PBS with 0.09% sodium azide; pH 7.4
• Gene Accession No.: Q96IY4
• Gene Symbols: CPB2
• Immunogen: Purified, full length, native human protein.
• Quantity: 200 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Affinity Purification, ELISA, Western Blot
• Clone: 19E2
• Conjugate: Unconjugated
• Gene: CPB2
• Gene Alias: 1110032P04Rik; 4930405E17Rik; AI255929; carboxypeptidase B2; carboxypeptidase B2 (plasma); carboxypeptidase B2 (plasma, carboxypeptidase U); carboxypeptidase B-like protein; carboxypeptidase R; Carboxypeptidase U; Cpb2; CPR; CPU; pCPB; Plasma carboxypeptidase B; Tafi; thrombin-activable fibrinolysis inhibitor; thrombin-activatable fibrinolysis inhibitor
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 1361
• Content And Storage: 4° C
• Form: Liquid