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Invitrogen™ Carbonic Anhydrase VIII Polyclonal Antibody

Description
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
The protein encoded by this gene was initially named CA-related protein because of sequence similarity to other known carbonic anhydrase genes. However, the gene product lacks carbonic anhydrase activity (i.e., the reversible hydration of carbon dioxide). The gene product continues to carry a carbonic anhydrase designation based on clear sequence identity to other members of the carbonic anhydrase gene family. The absence of CA8 gene transcription in the cerebellum of the lurcher mutant in mice with a neurologic defect suggests an important role for this acatalytic form.
Specifications
Specifications
| Antigen | Carbonic Anhydrase VIII |
| Applications | Immunohistochemistry (Paraffin), Western Blot |
| Classification | Polyclonal |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.2 |
| Gene | Ca8 |
| Gene Accession No. | P28651, P35219 |
| Gene Alias | AW546993; Ca8; Cals; Cals1; CAMRQ3; Car8; carbonate dehydratase; carbonic anhydrase 8; carbonic anhydrase VIII; carbonic anhydrase-like sequence; carbonic anhydrase-like sequence 1; carbonic anhydrase-related protein; CA-related protein; CARP; CA-RP; CARP VIII; CA-RP VIII; CA-VIII; hypothetical protein LOC550233; LOW QUALITY PROTEIN: carbonic anhydrase-related protein; MGC120502; MGC99509; wdl; zgc:110118 |
| Gene Symbols | Ca8, Car8 |
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