Invitrogen™ Carbonic Anhydrase VB Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA552959

Product Code. 15720911

Description

Immunogen sequence: GLAVIGVFLK LGKHHKELQK LVDTLPSIKH KDALVEFGSF DPSCLMPTCP DYWTYSGSLT TPPLSESVTW IIKKQPVEVD HDQLEQFRTL LFTSEGEKEK RMVD Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 98%.

Carbonic anhydrases (CAs) are members of a large family of zinc metalloenzymes responsible for catalyzing the reversible hydration of carbon dioxide.CAs show extensive diversity in their distribution and subcellular localization.They are involved in a variety of biological processes, including calcification, bone resorption, respiration, acid-base balance and the formation of aqueous humor, saliva, gastric juice and cerebrospinal fluid. CA VB, also known as carbonate dehydratase VB, is one of two isoforms of CA V. It localizes to the mitochondria and is involved in metabolic processes. CA VB is predominantly expressed in heart, pancreas, lung, placenta, kidney and skeletal muscle. It exhibits highest homology with family member CA VA (the second isoform of CA V); however, unlike CA VA, it is not expressed in the liver, suggesting that it plays a significantly different physiological role.

Specifications

• Antigen: Carbonic Anhydrase VB
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CA5B
• Gene Alias: 7330410H16Rik; Ca5b; Car5b; Carbonate dehydratase VB; carbonic anhydrase 5B; carbonic anhydrase 5b, mitochondrial; Carbonic anhydrase VB; carbonic anhydrase VB, mitochondrial; carbonic dehydratase; CarVb; CAVB; CA-VB; D730005F19Rik
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 11238
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 0.1 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9Y2D0
• Gene Symbols: CA5B
• Immunogen: Recombinant protein corresponding to Human Carbonic Anhydrase VB. Recombinant protein control fragment (Product #RP-92233).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG