missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Protein Analysis Reagents
  4. Bioactive Small Molecules
  5. Tocris Bioscience™ Capzimin dimer

Tocris Bioscience™ Capzimin dimer
GREENER_CHOICE

Product Code. 18785486
Change view
Click to view available options
Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
2 product options available for selection
Product selection table with 2 available options. Use arrow keys to navigate and Enter or Space to select.
Product Code. Quantity unitSize
18785486 50 mg 50mg
18756206 10 mg 10mg
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 2 options available.
2 options
This item is not returnable. View return policy
Product Code. 18785486 Supplier Tocris Bioscience™ Supplier No. 6781/50

Please to purchase this item. Need a web account? Register with us today!

This item is not returnable. View return policy

Description

Selective proteasome inhibitor

Capzimin dimer is a specific inhibitor of proteasome isopeptidase Rpn11 (IC50 = 2.1 μM and 3.8 μM, in 293T and A549 cell lines, respectively). It exhibits 80-fold selectivity for Rpn11 over Csn5, ten-fold over AMSH and six-fold over BRCC36 (IC50 = 30 μM, 4.5 μM, and 2.3 μM, respectively). Capzimin dimer blocks proliferation of cancer cells.
TRUSTED_SUSTAINABILITY

Specifications

Chemical Name or Material 8,8 '-Dithiobis[N-[2-(2-thiazolyl)ethyl]-3-quinolinecarboxamide]
CAS 2084868-04-0
Quantity 50 mg
Target Proteasome Inhibitors
Molecular Formula C30H24N6O2S4
Purity 0.98
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.