Capsazepine, 98+%, Thermo Scientific™

Product Code	Brand	Quantity
15405329	Thermo Scientific Alfa Aesar J63055.MA	10mg
15415329	Thermo Scientific Alfa Aesar J63055.MF	50mg

Description

This Thermo Scientific brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific.

Applications
Capsazepine is shown to inhibit the development of mechanical hyperalgesia induced by intraplanar capsaicin injection. Capsazepine is described to block Resiniferatoxin (sc-24015)- and Capsaicin-induced contractions of guinea pig treacheal smooth muscle. Studies investigating the function of the VR1 (TRPV1 receptor) have employed Capsazepine as a tool for perturbing systemic neuronal response to Capsaicin.

Solubility
Soluble in ethanol or DMSO

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: -20°C. Keep away from strong oxidizing agents.

Chemical Identifiers

• CAS: 138977-28-3
• Molecular Weight (g/mol): 376.899
• InChI Key: DRCMAZOSEIMCHM-UHFFFAOYSA-N
• PubChem CID: 2733484
• IUPAC Name: N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-1,3,4,5-tetrahydro-2-benzazepine-2-carbothioamide

• Molecular Formula: C19H21ClN2O2S
• MDL Number: MFCD00153778
• Synonym: capsazepine, capsazepin, n-2-4-chlorophenyl ethyl-1,3,4,5-tetrahydro-7,8-dihydroxy-2h-2-benzazepine-2-carbothioamide, unii-lfw48my844, n-2-4-chlorophenyl ethyl-7,8-dihydroxy-1,3,4,5-tetrahydro-2-benzazepine-2-carbothioamide, 2-2-4-chlorophenyl ethylamino-thiocarbonyl-7,8-dihydroxy-2,3,4,5-tetrahydro-1h-2-benzazepine, n-2-4-chlorophenyl ethyl-7,8-dihydroxy-1,3,4,5-tetrahydro-2h-2-benzazepine-2-carbothioamide, capasazepine, tocris-0464
• ChEBI: CHEBI:70773
• SMILES: C1CC2=CC(=C(C=C2CN(C1)C(=S)NCCC3=CC=C(C=C3)Cl)O)O

Specifications

• CAS: 138977-28-3
• MDL Number: MFCD00153778
• Solubility Information: Soluble in ethanol or DMSO
• SMILES: C1CC2=CC(=C(C=C2CN(C1)C(=S)NCCC3=CC=C(C=C3)Cl)O)O
• Molecular Weight (g/mol): 376.899
• ChEBI: CHEBI:70773
• Percent Purity: ≥99%

• Molecular Formula: C19H21ClN2O2S
• Synonym: capsazepine, capsazepin, n-2-4-chlorophenyl ethyl-1,3,4,5-tetrahydro-7,8-dihydroxy-2h-2-benzazepine-2-carbothioamide, unii-lfw48my844, n-2-4-chlorophenyl ethyl-7,8-dihydroxy-1,3,4,5-tetrahydro-2-benzazepine-2-carbothioamide, 2-2-4-chlorophenyl ethylamino-thiocarbonyl-7,8-dihydroxy-2,3,4,5-tetrahydro-1h-2-benzazepine, n-2-4-chlorophenyl ethyl-7,8-dihydroxy-1,3,4,5-tetrahydro-2h-2-benzazepine-2-carbothioamide, capasazepine, tocris-0464
• InChI Key: DRCMAZOSEIMCHM-UHFFFAOYSA-N
• IUPAC Name: N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-1,3,4,5-tetrahydro-2-benzazepine-2-carbothioamide
• PubChem CID: 2733484
• Formula Weight: 376.9
• Chemical Name or Material: Capsazepine

Safety and Handling

missing translation for 'tsca' : No

Recommended Storage : Ambient temperatures

RUO – Research Use Only