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DiscoverX cAMP Hunter™ CHO-K1 FPR1 Gi Cell Line

Product Code. 17394659
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Quantity:
2 Vials
Unit Size:
2 ampoules
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Product Code. Quantity unitSize
17394659 2 Vials 2 ampoules
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Product Code. 17394659 Supplier DiscoverX Supplier No. 950139C2

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Description

The cAMP Hunter™ CHO-K1 FPR1 Gi Cell Line measures FPR1 (GPCR) activity via decreased levels of intracellular cAMP. This cell line ships as two vials of cryopreserved cells.

The cAMP Hunter FPR1 Gi cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand based activation of FPR1 GPCR activity via detection of decreasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wildtype FPR1, a naturally Gi/Go coupled GPCR. Upon activation of FPR1, the decrease in levels of intracellular cAMP leads to a decreased signal from EFC when the cAMP detection kit is applied. This stable modified cell line is provided as two vials of cryopreserved cells.

Specifications

Assay Entry Intracellular cAMP level
Cell Line CHO-K1
For Use With (Application) Cell Lines
Primary Agonist WKYMVm-NH2
Quantity 2 Vials
Target Entry FPR1
Accession Number NM_002029
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