Invitrogen™ CaMKK alpha Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA578908

Product Code. 15944485

Description

Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: Rat Brain Tissue, Rat Brain Tissue, Mouse Brain Tissue, Mouse Brain Tissue, rat brain tissue, mouse brain tissue, human U-87MG whole cell. IHC: Rat Brain Tissue.

CAMKK1 (CAMKKA) is a serine/threonine protein kinase family member, and belongs to the Ca2+/calmodulin-dependent protein kinase subfamily. The product of CaMKK alpha is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. CAMKK1 functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Five transcript variants encoding distinct isoforms have been identified for CaMKK alpha. Different isoforms of this protein may regulate inducible expression of different cytokine genes.

Specifications

• Antigen: CaMKK alpha
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CAMKK1
• Gene Alias: AI846603; alpha CaMKK; calcium calmodulin dependent protein kinase kinase alpha; calcium/calmodulin dependent protein kinase kinase 1; calcium/calmodulin-dependent protein kinase kinase 1; calcium/calmodulin-dependent protein kinase kinase 1, alpha; calcium/calmodulin-dependent protein kinase kinase alpha; CaM-kinase IV kinase; caM-kinase kinase 1; caM-kinase kinase alpha; Camkk; caMKK 1; caM-KK 1; caMKK alpha; CaM-KK alpha; CAMKK alpha protein; CAMKK1; CAMKKA; CaMKKalpha
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 55984, 60341, 84254
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 500 μg/mL
• Formulation: PBS with 5mg BSA and 0.05mg sodium azide, 0.05mg thimerosal
• Gene Accession No.: P97756, Q8N5S9, Q8VBY2
• Gene Symbols: CAMKK1
• Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of mouse CaMKK (10-31aa QDPRAELVDRVAAINVAHLEEA).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG