Calpastatin Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 12250-1-AP-20UL

Product Code. 16839853

Description

The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described.

Specifications

• Antigen: Calpastatin
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CAST
• Gene Alias: BS 17, Calpain inhibitor, calpastatin, CAST, Sperm BS 17 component
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 831
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry, Immunoprecipitation, Immunohistochemistry (Paraffin), Immunofluorescence
• Concentration: 0.25 mg/mL
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Accession No.: P20810
• Gene Symbols: CAST
• Immunogen: Calpastatin Fusion Protein Ag2897
• Quantity: 20 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG