Calpastatin Monoclonal Antibody (A6B1), Invitrogen™

Mouse Monoclonal Antibody

Brand:  Invitrogen MA544975

Product Code. 17836872

Description

Calpastatin is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins.

Specifications

• Antigen: Calpastatin
• Classification: Monoclonal
• Concentration: 2 mg/mL
• Formulation: TBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: P20810
• Gene Symbols: Cast
• Immunogen: Recombinant protein within human Calpastatin aa 501-708/708.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Form: Liquid

• Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
• Clone: A6B1
• Conjugate: Unconjugated
• Gene: Cast
• Gene Alias: BS-17; Calpain inhibitor; calpastatin; calpastatin isoform III; calpastatin precursor (EC 3.4.22.17); calpastatin type 1; calpastatin type 2; calpastatin type 3; calpastatin type I; calpastatin type II; calpastatin type III; calpastatin type IV; Cast; Erythrocyte calpastatin; heart calpastatin; PLACK; Sperm BS-17 component; type III calpastatin
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 831
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Isotype: IgG1