Invitrogen™ Calpain S1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA531110

Product Code. 13425627

Description

Recommended positive controls: 293T. Predicted reactivity: Mouse (89%), Pig (97%), Rabbit (96%), Bovine (94%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Calpains are a ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. Calpain families have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. Calpain I and II are heterodimeric with distinct large subunits associated with common small subunits, all of which are encoded by different genes. Calpain S1 is a small subunit common to both calpain I and II and is associated with myotonic dystrophy.

Specifications

• Antigen: Calpain S1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: CAPNS1
• Gene Alias: 30K; Calcium-activated neutral proteinase small subunit; calcium-dependent protease; Calcium-dependent protease small subunit; Calcium-dependent protease small subunit 1; calcium-dependent protease, small subunit; calpain 4; calpain 4, small subunit (30K); calpain II regulatory subunit; calpain II regulatory subunit (EC 3.4.22.17); calpain regulatory subunit; Calpain small subunit 1; calpain, small polypeptide; calpain, small subunit 1; CALPAIN4; CANP; CANP small subunit; CANPS; Capa4; Capa-4; Capn4; CAPNS; CAPNS1; CDPS; CSS1; D7Ertd146e; small pol; unknown protein
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 826
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: P04632
• Gene Symbols: CAPNS1
• Immunogen: Recombinant protein encompassing a sequence within the center region of human Calpain S1. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG